If you are not a HCP, please click here

Intended for UK Healthcare Professionals.

The prescribing information link and adverse event reporting statement are found at the bottom of this page.

Midazolam Protocol Resources
If you are not a HCP, please click here

Intended for UK Healthcare Professionals.
The prescribing information link and adverse event reporting statement are found at the bottom of this page.

Midazolam Protocol Resources

Access

Access

Getting Epistatus® on formulary

Epistatus® is indicated for the treatment of prolonged, acute, convulsive seizures in adults, infants, children and adolescents aged 3 months and above*. Epistatus® must only be used by parents / caregivers where the patient has been diagnosed to have epilepsy.1-4 If Epistatus® is not yet on your local prescribing formulary, the following resources may be of use:
  • SmPC
  • Formulary pack (available from your local representative)
If you would like any assistance in preparing a case for formulary inclusion, your SERB Pharmaceuticals medical representative is available to help and advise as needed. Please click here to request a meeting.

*For infants between 3-6 months of age treatment should be in a hospital setting where monitoring is possible and resuscitation equipment is available

References:

  1. Epistatus® 2.5 mg Oromucosal Solution Summary of Product Characteristics (SmPC).
  2. Epistatus® 5 mg Oromucosal Solution SmPC.
  3. Epistatus® 7.5 mg Oromucosal Solution SmPC.
  4. Epistatus® 10 mg Oromucosal Solution SmPC.

UK-EPI-2400076

Date of Preparation: November 2024

How to prescribe Epistatus®

Midazolam is a schedule 3 controlled drug. This means there are some specific requirements when writing a prescription for Epistatus®:1

 

  • Include the patient’s title, forename, surname, address and age

 

  • State the name and form of the drug, strength of the preparation, and dose to be taken

 

  • The total quantity to be dispensed (or number of dose units e.g. 10 mg/1 mL x 2) must be written in both letters and numerals

 

  • The prescriber’s signature must be handwritten. (Note that since 2005 it is no longer mandatory
    for the rest of the prescription to be hand-written; this may be computer-generated)

 

  • The prescription is only valid for 28 days after the appropriate date

 

A fictitious example of a correctly filled-in prescription is provided for your convenience.

Community pharmacists can obtain Epistatus® pre-filled syringes exclusively via Alliance Healthcare. Hospitals can order Epistatus® pre-filled syringes directly from SERB Pharmaceuticals. For further information please contact SERB Pharmaceuticals here.

References:

  1. Government of the United Kingdom (2022) ‘List of most commonly encountered drugs currently controlled under the misuse of drugs legislation’. Available at: https://www.gov.uk/government/publications/controlled-drugs-list–2/list-of-most-commonly-encountered-drugs-currently-controlled-under-the-misuse-of-drugs-legislation (Accessed: October 2024).

UK-EPI-2400076

Date of Preparation: November 2024

Government help with funding

Unfortunately, patients with epilepsy may have significant ongoing health-related expenses, for instance due to prescription costs, transport to recurring clinic appointments, etc. In addition, physical and/or psychosocial factors may impact negatively on educational and employment opportunities. People with epilepsy are therefore at a higher risk of financial disadvantage.

There are a number of provisions in place, which may be of help to patients and to their families, including medical exemption certificates, prescription prepayment certificates, tax credits and travel cost reimbursement schemes. Some of these are means-tested, whilst others are universally available.

Further information is available via the following:

 

 

 

 

In order to claim some of this government assistance, your patient will need you to complete and sign a medical exemption certificate.

UK-EPI-2400076

Date of Preparation: November 2024

Seizures:
The Facts

Epistatus® in Paediatric Care

Epistatus® in Adult Care

Resources

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